Microbiological in vitro effect of glass ionomer cement enriched with chlorhexidine

Alex Tadeu Martins, Fabiano Sant Ana Santos, Juliana Rico Pires, Fábio Luiz Ferreira Scannavino, Marilia Valejo Gil

Resumo


ABSTRACT
Objective: The objective of the present study was to evaluate the microbiological effectiveness of the glass ionomer cement added by 1% chlorhexidine diacetate. Methods: The antimicrobial activity was performed through the test of halo formation to inhibit Streptococcus mutans (S. mutans), Staphylococcus aureus (S. aureus) and Candida albicans (C. albicans) in the following groups: Group 1: glass ionomer cement (GIC), Group 2: GIC added by 1% chlorhexidine diacetate, Group 3: chlorhexidine digluconate solution at 0.12% and Group 4: chlorhexidine digluconate solution at 2%. The halo inhibition area was measured in square millimeter (mm²), at 24 and 48 hours after incubation (37o.C). Results: The chlorhexidine digluconate solution at 2% (group 4), used as a positive control had a significantly higher antimicrobial effect than the other groups (groups 1, 2 and 3) and against all the microorganisms tested (p<0.01, Kruskal-Wallis test). The glass ionomer cement added by 1.0% chorhexidine diacetate (group 2) showed a statistically higher antimicrobial effect against S. aureus and S. mutans species than groups 1 and 3 (p<0.01). Conclusion: It was concluded that the addition of 1% chlorhexidine diacetate enriched GIC functions demonstrated by the effectiveness in growth inhibition of Streptococcus mutans and Staphylococcus aureus.


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