Upper lateral incisor agenesis is characterized by the absence of dental elements and can be a challenge for professionals regarding treatment possibilities, especially in deciduous dentition where it occurs less frequently. The aim of this report was to describe a case about the agenesis of maxillary lateral incisors in deciduous and permanent dentition. A child of 02 years and 04 months old attended the dental office with his mother. During the evaluation, the mother's main complaint was the aesthetic compromise due to the appearance of her daughter's smile, the radiographic examination was observed in the absence of the deciduous dental elements and permanent germs. This article discusses which treatment alternatives offer better quality of life due to negative aesthetic impact, as well as related social, economic and psychological aspects.